Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections (PANDAS) and Pediatric Acute-onset Neuropsychiatric Syndrome (PANS) have been suggested to be a result of a disordered immune response after an infection causing neuropsychiatric symptoms. An association with a group A beta-hemolytic streptococcus (GAS) infection is suggested in PANDAS and an association with other infectious agents in PANS. Although the diagnosis PANDAS/PANS has been controversial, more focus has come on the diagnosis, pathophysiology and treatment during the recent years.
The aim of this study is to increase knowledge about the etiology, diagnostic possibilities, treatment, prognosis and quality of life of children and adolescents with suspected PANDAS/PANS. All children and adolescents with suspected PANDAS/PANS from the whole country will be included. Participants will be examined with several diagnostic instruments, blood samples, neuropsychological test battery, and MRI scan of the brain.
Autum 2018 - autum 2021
Ongoing application to funds.